Top 20 most expensive prescription drugs in 2022


If you thought inflation was high, wait until you hear about rising specialty drug prices. A recent AARP report indicates that they are increasing at more than three times the rate of inflation. To see how you’ll be affected, we’ve put together this list of the 20 most expensive prescription drugs in 2022.

Rising drug costs are heartbreaking because prescription drugs were already expensive. Luckily, we’ve found a way to save up to 80% on your prescriptions. Tap or click here to see Kim’s favorite way to save money at the drugstore.

Depending on the medications you need, your prescriptions could cost thousands of dollars, reports AARP. Review the list below to see if any of your medications are listed. If so, brace yourself for tough financial times ahead.

These are the 20 most expensive prescription drugs in 2022

Worried about needing to buy the most expensive drug in the United States? It’s an understandable fear. When you hear about inflation impacting prescription costs, you can start Googling “List of Expensive Drugs,” “Highest Prescription Drugs,” or “Expensive Prescription Drugs in the U.S. ” to see if you have any problems.

Don’t waste hours researching. Use this helpful tip as a starting point. After all, we always have what you need here at Komando HQ. We also tell you which critical mistakes you should avoid, like these 10 worst ways to save money.

Scroll down to see the most expensive common prescription drugs in the US

Thanks to our sponsor GoodRx for the data. (More on that later.)

Drug name Maker What it treats Monthly cost (based on duration of treatment)
Zokinvy Eiger BioPharmaceuticals Hutchinson-Gilford syndrome progeria, which causes premature aging $89,480
Myalept Amryt Pharmaceuticals, Inc. Leptin deficiency in people with generalized lipodystrophy $77,496
Mavenclad EMD Serono, Inc. Multiple sclerosis $63,993
Ravicti Therapeutic Horizon Urea cycle disorders $57,998
Actimmun Therapeutic Horizon Osteopetrosis and chronic granulomatous disease $55,310
Oxervate Domped Neurotrophic keratitis, which makes the corneas less sensitive $50,874
Takhzyro Takeda Angioedema, a condition that causes swelling under the skin $48,233
juxtapid Amryt Pharmaceuticals, Inc. Homozygous familial hypercholesterolemia, which can lead to heart disease $47,897
Gatex Takeda Short bowel syndrome $42,913
Chenodal Travere Therapeutic Gallstones $42,570
Acthar Gel Mallinckrodt Pharmaceuticals Lupus, rheumatoid arthritis, multiple sclerosis, infantile spasms, eye conditions and psoriatic arthritis $41,459
Orladeyo BioCryst Pharmaceuticals Hereditary angioedema $38,427
Tegsedi Akcea Therapeutic Nerve damage caused by hereditary transthyretin amyloidosis $36,707
Ayvakit Medication Master Plan Gastrointestinal stromal tumors $35,213
Qinlock Decipher Pharmaceuticals, LLC Tumors of the gastrointestinal tract $35,199
Korlym Therapeutic Corcept High levels of cortisol in the body $34,620
Vitrakvi Bayer Pharmaceuticals Cancerous tumors with abnormally fused genes $33,784
Recorlev Xeris Pharmaceuticals, Inc. Endogenous Cushing’s syndrome (decreases the amount of cortisol in the body) $32,400
cortrophin gel ANI Pharmaceuticals, Inc. Rheumatic disorders, collagen diseases and dermatological diseases $31,851
Tibsovo Servier Pharmaceutical Acute myeloid leukemia, blood and bone marrow cancer $30,083
Data from GoodRx, our sponsor.

Have you seen any familiar names on that US drug price list? Unfortunately, you need one of the most expensive prescription drugs.

All hope is not lost

You can still save money on the most expensive popular generic drugs. You can talk to your doctor about sample packs, check out mail-order pharmacies, or research government assistance programs. Tap or click here for five ways to save money on your prescription (or get it for free).

Never think you are alone. There are free ways to save money on lifesaving drugs. We haven’t even figured out the best way to save money on prescription drugs. There’s also a free database you can use to find discounts. (Kim love this!)

Save money on the most expensive prescription drugs in the US

So you’ve just looked at our list of the most expensive prescription drugs. You’re starting to feel nervous since you saw your prescription on it. Take a deep breath and get ready for a silver lining.

Use GoodRx to get your medications at the best price. To find deep discounts, search for your drugs in its search bar and see what prices you can find at nearby pharmacies. You don’t need to register or share any personal information: This is a free tool that compiles the various prescription prices you can find in pharmacies across America.

Use this link to let GoodRx know that Kim sent you there. No matter how much inflation makes your prescription prices skyrocket, you have a safe place to land. GoodRx offers deep discounts on expensive prescription drugs, so you can have peace of mind when shopping.

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